Villarreal x Napoli
Villarreal have only lost one home game all season in league and European competition. Napoli's run of eight straight wins in the league came to an end when they were beaten 1-0 by Juventus at the weekend. The Italian's are favourites on paper, but much will depend on the strength of the two starting line-ups, with Napoli manager Sarri so far opting to field weakend teams in Uefa's second competition. Napoli won each of the last two meetings between these sides 2-0, but they have not faced off against each other since 2011.
Prediction: Villarreal DNB
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